Home / What We Do / ALOFT Study
ALOFT-Assessing the Durability of Uterine Sparing Procedures and Quality of Life
A strength of ALOFT is that we utilized the infrastructure of COMPARE UF to extend long-term follow-up of women following uterine sparing procedures for symptomatic uterine fibroids. In ALOFT, we are following ~1300 women up to 7-10 years following their index procedure to assess the impact on symptoms.
Gestational Diabetes Mellitus (GDM) affects 7-10% of pregnancies GooDMomS is a digital health pregnancy and postpartum lifestyle intervention for women with recent GDM to promote glucose control during pregnancy and weight loss after delivery. Our goal is to use digital health technology to advance perinatal health, promote the health of the mother-child dyad, and test the acceptability of an intervention that can be integrated alongside routine clinical obstetrical care.
By age 50, 50% of white women and 70% of black women will have symptomatic uterine fibroids. COMPARE UF is a prospective longitudinal study measuring quality of life outcomes following surgical intervention for uterine fibroids.
Our overall goals were to establish a national registry of women undergoing surgical interventions for uterine fibroids, to conduct a longitudinal follow-up of women following surgical interventions, assess women’s perception of their quality of life (QoL) following hysterectomy (removal of uterus) versus uterine sparing procedures (myomectomy, UAE, endometrial ablation). We found that women undergoing either hysterectomy or myomectomy had improved QoL scores, although those undergoing hysterectomy had slightly higher scores. Additionally, those with hysterectomy had better symptom severity scores and more improved depression scores.
This study aimed to develop and rigorously evaluate an online platform—the DiabetesSisters Network—to engage women with current or gestational diabetes. The goal was to create a virtual patient community that empowers participants to identify and prioritize topics for patient-centered and comparative effectiveness research.
